Beware of pain-relieving drugs

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NSAIDs are a group of medicines, including aspirin, ibuprofen, diclofenac, indomethacin, ketorolac, sulindac, lornoxicam, meloxicam, piroxicam, tenoxicam, naproxen, mefenamic acid, celecoxib, rofecoxib, parecoxib, and valdecoxib.

The medicines are used for pain-relieving and fever-reducing effects. They are available both over-the-counter (OTC) and on prescription upon consultation with a doctor.

They are also available both as single medicines and in combination with other medicines.

While considered safe when taken as directed, SAHPRA warned that NSAIDs can cause stomach bleedings, may reduce kidney function, and may occasionally lead to heart attack or stroke.

“These risks are higher with higher doses and/or longer than recommended period of use of NSAIDs and in patients who have pre-existing stomach problems, or have heart or kidney diseases. If you take low-dose aspirin for protection against heart attack and stroke, be advised that some NSAIDs can interfere with that protective effect.

“If you have heart disease or high blood pressure, consult a healthcare provider before using an NSAID. Please inform your health care provider of any existing heart condition or known kidney problems or pre-existing stomach condition when seeking treatment,” SAHPRA said.

SAHPRA added that prescription NSAIDs are an important treatment for the symptoms of many debilitating conditions, including osteoarthritis, rheumatoid arthritis‎, gout and other rheumatological and painful conditions.

“OTC NSAIDs are used to temporarily reduce fever and to treat minor aches and pains such as headaches, toothaches, backaches, muscular aches, tendonitis, and strains.”

Consumers are urged to read the patient information leaflet for both OTC and prescription medicines, as it provides important safety information.

SAHPRA advises consumers to seek medical help if they experience stomach bleeding or symptoms that might signal heart problems or stroke, such as chest pain, trouble breathing, sudden weakness in one part or side of the body, or sudden slurred speech while on NSAIDs.