Proton therapy offers life-changing benefits to children with cancer

The Children's Hospital of Philadelphia announces the availability of proton therapy, a precise form of cancer radiation that offers potentially life-changing benefits to children with brain tumours and other solid tumours. The Hospital's Cancer Centre has recently begun using proton treatment at the new Roberts Proton Therapy Centre, a cutting-edge radiation oncology facility located across the street from Children's Hospital in Penn Medicine's Perelman Centre for Advanced Medicine.

With a child diagnosed with a brain tumour, parents often face a cruel dilemma. Conventional radiation treatment that offers survival often risks severe side effects, including damage to surrounding healthy tissue, as well as impairments to hearing, vision, growth and cognition. The after-effects may impede a child's daily life and may carry the prospect of lifelong disability and dependence. In fact, the side effects are potentially devastating enough that conventional radiation therapy is not given to children under age two.

Planned for paediatric focus

The Roberts Proton Therapy Centre is the only proton therapy facility in the country conceived with paediatric patients in mind from the earliest planning stages. Children who receive proton therapy in this $140 million state-of-the-art facility benefit from a long-standing collaboration between Children's Hospital and radiation oncologists at Penn Medicine. Young patients experience family-focused paediatric care from a medical team who understands the unique needs of children with cancer, while providing emotional support for the entire family. Every detail has been considered - from scheduling morning treatments for children who cannot eat prior to anaesthesia, to offering a dedicated child-oriented waiting room and a dedicated paediatric anaesthesia room.

"When the Roberts Proton Therapy Centre's paediatric program is fully operational, the Cancer Centre at Children's Hospital will be able to treat more children with proton therapy than all other American proton centres combined, thereby reducing the negative impact of cancer therapy for children from the Philadelphia region and around the country" said John M. Maris, M.D., chief of Oncology and director of the Cancer Centre at The Children's Hospital of Philadelphia.

All care available at one location

With its extensive program of comprehensive services, the Cancer Centre is one of the largest paediatric cancer programs in the United States. All cancer care is available at one location, including doctor's visits, lab work and a full range of therapies. In its most recent listings, U.S. News & World Report ranked Children's Hospital first in cancer care among America's children's hospitals.

In addition to its application for brain tumours, proton therapy may also be appropriate for cancers of the head and neck, and tumours located near the spinal cord, heart and lungs-sites perilously close to vital organs.

The advent of proton therapy provides a dramatic reduction in side effects when compared to conventional radiation. Because protons can be more precisely aimed and concentrated on a tumour, much less energy impacts normal tissue in front of and behind the cancerous mass. At the same time, doctors may increase the radiation dose focused on the tumour for optimum benefits.

Protons are positively charged particles, found in the nucleus of every atom, but made available in this therapy by stripping away electrons from hydrogen atoms. Although commonly manipulated by physicists in high-energy particle accelerators in research settings since the mid-20th century, protons are only gradually becoming part of medical practice. There are currently only seven proton therapy centres in the United States.

Source: Children's Hospital of Philadelphia