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| Display Mania International | Cape Town | Snap Frames, Pull-Up Banners, Light Boxes, Gazebos | |
| Distinctive Choice t/a Lie and Tell | Cape Town | Truth Verification | |
| Distribution Management Services | Cape Town | Business Management Consultant | |
| Divine Brand Intervention | Cape Town | Packaging Design, Corporate Indentity, POS design | |
| Divorce Lawyers Cape Town | Cape Town, | Divorce Lawyers Cape Town | |
| DJ's Model Agency | Cape Town | Casting Agency | |
| DLPHOTO | Cape Town | Photography School & Studio | |
| Dlphoto Photo Studios | CAPE TOWN | Photography services | |
| dmg Events | Johannesburg | Exhibitions | |
| DMH Talent Agency | Cape Town | Talent Management/Models/Actors/Singers/Dancers | |
| DNA Cleaning | Cape Town | Selling of natural cleaning products | |
| DNA Community | Cape Town | Business and Growth Hacking | |
| DNA Studios | Cape Town | film, television, corporate videos & animation | |
| Donald J. Trump Golden Check | New York | Golden Trump Check Reviews | |
| Donnelly Tool Hire | Hermanus | Donnelly Tool Hire | |
| Dont Speak Digital | Cape Town | Dont Speak Digital | |
| DonValley Brand Reputation Managers | Cape Town | Corporate/Brand Reputation Management Consultancy | |
| Door 6 Entertainment | Cape Town | Corporate Functions, Live Shows and Entertainment | |
| Doors and Drawers The Custom Wood and Steel Co. | Cape Town | Kitchens, Joinery, Steel and custom furniture | |
| DOT Effect Solutions | Cape Town | IT consulting | |
| DotActiv | Germiston | Category Management Software/Services | |
| Dotjam | Multi-channel strategic consultancy | ||
| Dowd Engravers Pezula signage solutions | Cape Town | industrial manufacturing, lasercutting, printing | |
| Down South Towing | Cape Town | 24 hour mechanical and breakdown service | |
| DPI Concepts | george | Branding | |
| Dr Alek Nikolic | Cape Town | 33 Piers Road Wynberg Cape Town | |
| Dr Andre De Villiers - Orthodontist | Cape Town | Orthodontist | |
| Dr JJ Serfontein | JJS Dentistry Cape Town | Cape Town | Dentistry | |
| Dr Kay U. Brugge | Cape Town | Life Coaching, Mentoring, Life Strategy | |
| Dr Leana van Dyk | Paediatrician | Cape Town | Medical Practice | |
| Dr Natalia Novikova | Cape Town | Gynaecologist | |
| Dr S Ranchod | Cape Town, South Africa | Maxillofacial and Oral Surgery | |
| Dr Sizwe Derrick Mthiyane | Richards Bay | Medical Practice | |
| Dr Sunil Thakersee | Cardiologist Cape Town | Cape Town | Medical Practice | |
| Dr Tanja Beeton Audiologist | Cape Town | Audiology | |
| Dragonfly Direct Marketing SA | Cape Town | Direct Marketing and Print Management Specialists | |
| Drawing Board Marketing | Cape Town | Marketing | |
| DREAM TEAM WORLD | Cape Town | Branded Entertainment specialists, reality tv | |
| Dreamcoatpainting | Umhlanga | Dreamcoat is a multi-disciplined professional. | |
| Dreams | Pringle Bay | Self catering holiday home 100m from beach, CT | |
| Dreamsmiths Digital | Cape Town | Software Development | |
| Dredging Sevices | Hermanus | Dredging | |
| Drive South Africa | Cape Town | Car rental, 4x4 rental, camper rental | |
| Driveshafts Centre | Cape Town | Driveshafts, Propshafts, Suspension, Steering Rack | |
| Driving Lessons Cape Town | Stellenbosch | Driving Lessons | |
| DryForce | Cape Town | Restoration | |
| DSA Window Cleaning | Somerset West | Window Cleaning | |
| Dstv Pro Technicians | We Do Dstv and Cctv Installations around all Weste | ||
| Ductworth Extraction Cleaning Services | Cape Town | Restaurant Extraction Servicing, Canopy Cleaning | |
| Durbanville Painters | Bellville | Painting Contractors | |
| Dutch Manor Antique Hotel | Cape Town | Accommodation | |
| Duvalele Luxury Tours and Travel | Airport transfers and shuttle | ||
| Dyeandprints (Sole Proprietor) | Uniondale | Online learning for textile enthusiasts | |
| Dynamic Designs | Paarl | Graphic & Web Design, Advertising & Branding | |
| Dynamikos | Bellville | Training and Services | |
| Dynamix Security Solutions | Cape Town | Installations | |
| E and K Logistics | Transportation | ||
| e l Concepts | Cape Town | Copywriting | |
| E-Classroom | Cape Town | School Online; Curriculum support Grades R-12 | |
| E-Tech Electronics | Cape Town | Electronics Repair company | |
| Easicompli | Durbanville | Company Registrations, CIPC Compliance | |
| East SSD Chemical Slab | money | ||
| Easy Beesy Auto Hives | Ceres | Beekeeping supplies | |
| Easy Grasse | Cape Town | Artificial Grass | |
| Easy Shade Ports | Bellville | At Easy Shade, we specialise in Shadeports for res | |
| EasyAs! Point of Sale Business Software | Cape Town | Point of Sale | |
| Eaton Consulting Services | Cape Town | BBBEE & HR Consulting Services | |
| Ebony+Ivory Ad Agency | Somerset West | Full service advertising agency | |
| EchoVine Communications | Durbanville | Content Marketing and Communication Strategists | |
| Eclipse Communications | Cape Town | Public Relations | |
| Eco D Wash South Africa | Cape Town | Manufacuring,marketing,franchising | |
| Eco Furniture Design | Cape Town | furniture store | |
| Eco Mobile Valet | Cape Town | Car wash | |
| Eco Slayer Cape Town | Cape Town | Eco friendly Pest, Insect, Bird and Rodent Control | |
| Eco Topia | Bellville | Organic and Eco-Friendly Products | |
| Eco Valet | Parow | Mobile Car Wash and Valet | |
| Eco-Logic Publishing - The Enviropaedia | Cape Town | Enviropaedia, Eco-Logic Awards | |
| EcoPack | Cape Town | Sustainable, compostable & biodegradable packaging | |
| Ed Unique | Strand | Peer Ed, HIV AIDS, Life Skills, Stress Management | |
| Eddie Goldberg Productions (EG Productions) | Cape Town | Video's for social media and radio ads and jingles | |
| Eden Lawns | Sedgefield | Grass sales | |
| Edge Multimedia | Cape Town | Digital Marketing in video, animation & design | |
| Ediify - Digital Marketing Courses In Vashi Navi Mumbai | Thane | EDIIFY - Digital Marketing Courses in Vashi | |
| Educat Publishers | Cape Town | School and office Stationery | |
| EE Consult | Cape Town | Employment Equity Act Specialists | |
| Effective Private Investigators Cape Town | Cape Town | Detectives/Private Detectives/Security | |
| EG Productions | Cape Town | Recording of video and audio material | |
| Eikenhoff Orchid Nursery | Stanford | Garden centre ยท Wholesale and supply shop | |
| Elan Polo S.A. | CAPE TOWN | Footwear Manufacturers, Importers and Suppliers. | |
| Electric Book Works | Cape Town | Web, mobile and print publishing | |
| Electric Sheep Creative Agency | Cape Town | Social Media Marketing | |
| Electrical Services Sandton | Sandton | Electrical services Sandton | |
| Elegant Perspex Displays | Cape Town | Perspex products and signage manufactured | |
| Element Recruitment | Cape Town | Specialist Recruitment Services | |
| elements | Table View | Self-catering Accommodation | |
| ELEMINT | Cape Town | Exercise Programmes | |
| Elevate Learning | Cape Town | Online Learning Consultancy |
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