Image: FreeDigitalPhotos.net
"I have the pleasure to announce the discovery of a compound which will be the first ever clinical candidate researched on African soil as part of a modern pharmaceutical industry drug discovery programme," she said in a statement.
The recently discovered compound, from the aminopyridine class, not only had the potential to become part of a single-dose cure for all strains of malaria, but might also be able to block transmission of the parasite from person to person, she said.
This followed a research collaboration involving the Medicines for Malaria Venture (MMV), based in Switzerland, and the Drug Discovery and Development Centre (H3-D) at UCT.
On the basis of initial results it had been selected by MMV for further development.
"The candidate molecule is novel, potent, and has the potential to have a significant impact on global malaria control and eradication," Pandor said.
The science and technology department had invested R25-million in this pioneering programme between MMV and UCT.
"This is a powerful demonstration of how much can be accomplished when open minded researchers come together for the sake of the greater good of humanity.
"The discovery that we announce today is a significant victory in the battle to alleviate the burden of disease in Africa.
"Clearly the war on disease is not yet won, but I am excited by the role that our excellent scientists have played in finding a potential single-dose cure for malaria and possibly preventing its transmission."
South Africa in general had built considerable strength in clinical research over the past decade. The main focus had been on HIV/Aids and TB.
This development had occurred together with significant growth in the basic sciences that underpinned infectious disease research (immunology, virology, microbiology, biochemistry, and genetics), Pandor said.
Source: Sapa via I-Net Bridge
For more than two decades, I-Net Bridge has been one of South Africa’s preferred electronic providers of innovative solutions, data of the highest calibre, reliable platforms and excellent supporting systems. Our products include workstations, web applications and data feeds packaged with in-depth news and powerful analytical tools empowering clients to make meaningful decisions.
We pride ourselves on our wide variety of in-house skills, encompassing multiple platforms and applications. These skills enable us to not only function as a first class facility, but also design, implement and support all our client needs at a level that confirms I-Net Bridge a leader in its field.
Go to: http://www.inet.co.za
